The individual molecular composition of the capsid proteins and RNA of the selected viruses confer distinct specificity and infectivity characteristics. These three viral entities were selected because of their different genomic and virion structures, surface isoelectric points, and their propensity to mutate. In our experiments, we exposed three strains of pathogenic viruses to silicon nitride, namely, Influenza A virus (A/Puerto Rico/8/1934 H1N1), Feline calicivirus, and Enterococcus 71 (EV-A71). “The impetus for testing silicon nitride against viruses was to extend our understanding of the unique surface chemistry of silicon nitride, and attendant antibacterial properties. Silicon nitride’s resistance to bacteria has been verified in several in vitro and animal studies that have been published by SINTX scientists, as well as by independent investigators.” Of interest is a particularly unique property of silicon nitride, i.e., its ability as a biomaterial to resist bacterial adhesion, a precursor to implant-related infections. Basic science and clinical data have repeatedly shown the efficacy and safety of silicon nitride as a spinal implant material. Sonny Bal, Chairman and Chief Executive Officer of SINTX, explained that “As background, SINTX manufactures spine implants made of silicon nitride these have been used in thousands of spinal fusion surgery patients for over ten years.
The US application is numbered US 2020/0779651 A1 and titled “Antipathogenic Devices and Methods Thereof.” The international application is numbered WO 2020/051004 A1 and titled “Antipathogenic Compositions and Methods Thereof.”ĭr. (NASDAQ: SINT) (“SINTX” or the “Company”), an original equipment manufacturer (OEM) ceramics company focused on silicon nitride applications, today announced that US and international patent applications were published on Main which certain claims made in the applications address the potential surface antiviral effect of silicon nitride. SALT LAKE CITY, UT, Ma(GLOBE NEWSWIRE) - SINTX Technologies, Inc.
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